[1]骆志坚 熊 念 王 涛 向明清 涂 强 黄 毅 成祥林 王 莉.三七总皂苷对高血压性脑出血患者 血肿吸收及神经功能恢复的影响[J].三才期刊采编系统演示平台,2015,1期(04):234-236.[doi:10.3969/j.issn.1007-0478.2015.04.011]
 Luo Zhijian,Xiong Nian,Wang Tao,et al.Effect of panax notoginseng saponins(PNS)on the absorption of hematoma and neurological function recovery in patients with hypertensive intracerebral hemorrhage[J].,2015,1期(04):234-236.[doi:10.3969/j.issn.1007-0478.2015.04.011]
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三七总皂苷对高血压性脑出血患者 血肿吸收及神经功能恢复的影响
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《三才期刊采编系统演示平台》[ISSN:1008-0341/CN:37-1280/R]

卷:
第1期
期数:
2015年04期
页码:
234-236
栏目:
论著
出版日期:
2015-12-31

文章信息/Info

Title:
Effect of panax notoginseng saponins(PNS)on the absorption of hematoma and neurological function recovery in patients with hypertensive intracerebral hemorrhage
文章编号:
1007-0478(2015)04-0234-04
作者:
骆志坚 熊 念 王 涛 向明清 涂 强 黄 毅 成祥林 王 莉
434000 湖北荆州市长江大学附属第一医院神经内科[骆志坚 向明清 涂 强(通信作者)黄 毅 成祥林 王 莉];
华中科技大学同济医学院附属协和医院神经内科(熊 念 王 涛)
Author(s):
Luo Zhijian Xiong Nian Wang Taoet al.
Department of Neurology, The First Hospital Affiliated to Yangtze University, Jingzhou 434000
关键词:
三七总皂苷 高血压性脑出血 血肿吸收 神经功能缺损
Keywords:
Panax notoginseng saponins Hypertensive intracerebral hemorrhage Absorption of hematoma Neurological deficit
分类号:
R743.34 R544.1
DOI:
10.3969/j.issn.1007-0478.2015.04.011
文献标志码:
A
摘要:
目的 观察三七总皂苷(PNS)对高血压性脑出血(HICH )血肿吸收及神经功能恢复的影响。方法 将入选的HICH患者120例随机分为PNS组(常规药物治疗加三七总皂苷)58例和对照组(常规药物治疗)62例; 所有入选患者分别于入组第 1、4、10、17 d利用CT测量血肿体积,并进行神经功能缺损评分(NIHSS)和日常生活活动能力评定(ADL)。对照组采用内科常规脑出血治疗方法,PNS组先采用常规药物治疗3 d,并于第4 d开始加用血塞通注射液(主要成分为PNS)0.4 g静滴,1次/d,连用14 d,于第10 d和第17 d进行疗效判定。结果 PNS组第10、17 d血肿体积均小于对照组(P<0.01); 第10 d神经功能缺损评分低于对照组(P<0.05),第17 d神经功能缺损评分低于对照组(P<0.01),日常生活活动能力分值均高于对照组(P<0.01)。结论 三七总皂苷能明显促进高血压性脑出血血肿的吸收,促进神经功能的恢复。
Abstract:
ObjectiveTo observe the effect of panax notoginseng saponins(PNS)on hematoma absorption and neurological function recovery in patients with hypertensive intracerebral hemorrhage(HICH).Methods The 120 HICH patients enrolled were randomly divided into two groups, PNS group(conventional drug treatment plus PNS)58 cases and the control group(conventional drug treatment)62 cases. Scanning hematoma volume by CT, the National Institutes of Health Stroke Scale(NIHSS)scores and activities of daily living(ADL), all the three methods were used on the 1st, the 4th, the 10 th and the 17 th day. Conventional medical treatment of cerebral hemorrhage was used in the control group. PNS group were treated with conventional drug therapy for three days, and on the fourth day plus XUESAITONG injection(with the main component of PNS)0.4 g infusion, 1 times/d, for 14 days. At the 10 th and the 17 th day, efficacy was determined.Results Hematoma volume of PNS group was less than that of the control group at the 10 th and the 17 th day. Neurological deficit scores were lower, while activities of daily living scores were higher.Conclusions PNS can significantly promote the absorption of hematoma as well as the recovery of neurological function in patients with HICH.

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备注/Memo

备注/Memo:
2014-12-31收稿
更新日期/Last Update: 2015-08-30